SCREEN Cell3iMagers are bright field scanners designed specifically to simplify and accelerate quantitative and qualitative measurement of 3D spheroids and organoids. These unique imaging systems allows the user to identify and measure single or multiple spheroids per well in a microplate rapidly and automatically. The companion 3D optimized analysis software allows faster image capture, measurement and data analysis, and is compatible with all major 3D cell culture platforms. To fit varying budgets and throughput needs, the imager is available in three models: the single-plate Cell3iMager Neo (cc-3000) or the four-plate Cell3iMager (cc-5000), the dual purpose (2D & 3D; bright-field & fluorescence) Cell3iMager Duos (cc-8000).

SCREEN also has a NEW Cell3iMager Estier 3D Imaging for live samples by using near-infrared ligth.  It is a stage-top optical coherence tomography (OCT) instrument that allows non-invasive analysis of the 3D structures including spheroids, organoids, tubular structures etc. As Estier OCT provides an advantageous platform to visualize the in vitro dynamics of the 3D spheroids conveniently, it can be used as an alternative visualization/monitoring method to obtain quantitative information about the morphological changes occur in 3D cell culture samples.

See below for more information on each Imager.

NEW Cell3iMager Estier a label-free, non-invasive 3D tomographic imaging tool to facilitate drug screening (up to 1 mm thick). Detects necrotic regions and quantifies volume, internal cavities and tubular structures with impressive focus. A cost-effective supplementary system to an existing imaging system
Download Cell3iMager Estier Product Sheet



Cell3iMager / Cell3iMager Neo High Speed 3D Cell Culture Scanners
These High Speed Imagers can scan a microplate just in 54 seconds, enables measuring of area, estimated volume, diameter and number of spheroids in next 30 seconds. They are reagent-free and label-free systems, eliminating a series of processes including reagent dropping, stirring and flourescence measuring.  They are simple and user friendly and compatible with microscope slides, dishes and various microplates.

Cell3iMager (four plate) is a bright field scanner, ideal for label-free assays of 3D cell cultures.  Compatible with various 3D culture plates, allows the use of 6-well to 384-well plates and 35mm dish.


Cell3iMager Neo (single plate) has a compact design, reduction in footprint by 40%. It provides excellent performance and scalability without compramising the functions of the Cell3iMager.  In less than 2 minutes per plate, Neo rapidly determines diameter, area, pseudo volume, and circularity of individual spheroids, non-invasively.  The fastest spheroid-optimized bright field imager at a price every lab can afford.
Download Cell3iMagers Product Brochure



Cell3iMager Duos is a high-throughput, high-resolution scanner for fast, label-free and whole-well imaging and quantification of 2D and 3D cell culture. It enables both bright-field and multi-channel fluorescence imaging (up to 5 channels) and analysis. With its unique hypercentric and telecentric optical system which comprises a 4.2 megapixel area sensor and LED- strobing light system,

Cell3iMager Duos is designed to overcome the throughput limitations as well as complexities of microscopy. Duos enables simple growth and morphological profiling to more complex analyses such as fluorescence imaging, Z-stacking/focus-bracketing, high-resolution image capturing, and long-term live cell imaging. Escape speed and throughput limitations and focus more on your data. Watch Video Below
Download Cell3iMager Duos Product Brochure


3D Cell Culture Scan/Imaging Key Research Applications: Phenotypic Drug Discovery, Drug Sensitivity Testing, Co-culture: Lossof Spheroid Volume, Drug target Discovery and Validation and Quality Control.  Cell Prolliferation and Cytotoxicity Assays, 2D & 3D Celllular Imaging and Analysis, Combinatorial Drug Testing, Drug-Target Discovery and Validation, Quality Control of Adherent and Suspension Cell Culture, Antibody Development and Regenerative Medicine.

Application Notes:
Anticancer Drug Screening Method
Rapid Production and Size Assesment of EB’s
Study Complex 3D MCTS Models

Contact us for more information.

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